師資
基本概況:
張斌田,南方科技大學環境科學與工程學院副教授(研究員,博士生導師,獨立PI), 深圳市城市環境健康風險精準測量與預警技術重點實驗室副主任。本科畢業于南開大學,博士畢業于中科院生態中心,先后在中科院福建物構所及美國亞利桑那州立大學從事研究工作,入選國家級海外青年人才及深圳市孔雀特聘崗位。主要研究方向為環境分析化學及生物傳感技術,圍繞新污染物的快速檢測、污染物的毒性效應篩查以及分子毒理學研究,發展高靈敏的生物分析方法、生物傳感器及便攜式檢測器件和設備等。主持國家自然科學基金面上等多項國家級和省市級項目。在PNAS、JACS、ACS Nano、Nano Letters、AC等國際知名學術期刊發表論文40余篇,申請及獲批國際專利(PCT)、美國和中國專利8項,實現專利技術轉讓2項。曾獲第一屆“新污染物治理青年創新獎”、“亞利桑那州立大學技術轉讓優秀獎”、“ACS 特殊貢獻獎”等獎勵。擔任SCI期刊Environ. Sci. Nano副主編、中國環境科學學會新污染物治理專業委員會委員。
工作經歷:
2022 - 至今 南方科技大學 副教授(PI,研究員)
2021 - 2022 南方科技大學 助理教授(PI,副研究員)
2016 - 2021 亞利桑那州立大學 副研究員(合作導師:Stuart Lindsay教授)
2012 - 2016 中科院福建物質結構研究所 助理/副研究員(合作導師:林璋教授)
教育背景:
2007 - 2012 中科院生態環境研究中心,環境科學,博士學位(導師:郭良宏研究員)
2003 - 2007 南開大學,環境科學,學士學位 (導師:朱琳教授)
社會兼職:
1. 2024 - RSC《Environmental Science: Nano》副主編
2. 2023 - 中國環境科學學會新污染物治理專業委員會委員
獲獎及榮譽:
1. 2024:第一屆“新污染物治理青年創新獎”
2. 2024:RSC“視覺科研”封面大賽優秀導師獎
3. 2021:ACS特殊貢獻獎
4. 2020:《Sensors & Actuators: B. Chemical》優秀審稿人獎
2019:ASU技術轉讓優秀獎
研究方向:
1. 新污染物的快速檢測技術研發
2. 污染物毒性效應的篩查與檢測
3. 電化學/光電化學傳感器和微流控芯片
4. 原子力顯微鏡及掃描隧道顯微鏡的生物分析應用
5. 單分子電學檢測技術研究
6. 新型生物傳感器及便攜式檢測儀器研制
(歡迎具有環境科學、化學、材料等相關學科背景的同學報考碩士及博士研究生;課題組也長期招聘相關專業背景的博士后,一起合作探索有趣的研究課題?。?/strong>
代表性科研項目:
1. 2024 “深圳市多介質環境中典型新污染物的識別、暴露評估與健康風險管控”,深圳市科創委,深圳市高層次人才團隊項目(核心成員)
2. 2023 “用于基因毒性標志物8-羥基鳥嘌呤檢測的分子電導傳感器研究”,深圳市科創委,穩定支持面上項目(主持)
3. 2023 “基于單分子蛋白電導的內分泌干擾物與蛋白相互作用研究”,國家自然科學基金,面上項目(主持)
4. 2023 “城市大氣復合污染條件下神經退行性疾病的風險因子篩查控制技術研究與應用示范”,深圳市科創委,可持續發展科技專項(課題負責)
5. 2023 “深圳市城市環境健康風險精準測量與預警技術重點實驗室”,深圳市科創委,重點實驗室組建項目(學術帶頭人、副主任)
6. 2014 “基于分子印跡技術的光電化學傳感器檢測酚類內泌干擾物 ”,國家自然科學基金,青年項目(主持)
7. 2014 “基于ZnO納米花的光電化學傳感器研究”,福建省科學技術廳,青年項目(主持)
教學:
1. ESE336 - 環境分析化學(本科生)
2. ESE5096 - 環境生物分析化學(研究生)
學術成果:
代表性論文
(1) Shangqing Wang; Lulu Ma; Xiaonan Feng; Kun Zhang; Zheqian Chen; Min Hu; Guomao Zheng; Yan Zheng; Bintian Zhang, Portable and Cost-Effective Detection of Perfluorooctanesulfonate in Water Using a Screen-Printed Electrode Modified with Molecularly Imprinted Polymer. ACS ES&T Water 2025, 5, 1261-1269.
(2) Jingjing Yao; Xiaonan Feng; Shangqing Wang; Yuemei Liang; Bintian Zhang, Plasmon-Enhanced Photoelectrochemistry of Photosystem II on a Hierarchical Tin Oxide Electrode for Ultrasensitive Detection of 17β-Estradiol. Analytical Chemistry 2024, 96, 18029-18036.
(3) Zhimin Fan; Kun Zhang; Xiaonan Feng; Ya Hu; Zheqian Chen; Shangqing Wang; Jingfu Liu; Bintian Zhang, Portable and ultrasensitive detection of traces of water in alcoholic solvents by a polypyrrole-modified screen-printed electrode. Journal of Electroanalytical Chemistry 2024, 970.
(4) Tao Jiang; Biao-Feng Zeng; Bintian Zhang; Longhua Tang, Single-molecular protein-based bioelectronics via electronic transport: fundamentals, devices and applications. Chemical Society Reviews 2023, 52, 5968-6002.
(5) Bintian Zhang; Eathen Ryan; Xu Wang; Weisi Song; Stuart Lindsay, Electronic Transport in Molecular Wires of Precisely Controlled Length Built from Modular Proteins. ACS Nano 2022, 16, 1671-1680.
(6) Longhua Tang; Long Yi; Tao Jiang; Ren Ren; Binoy Paulose Nadappuram; Bintian Zhang; Jian Wu; Xu Liu; Stuart Lindsay; Joshua B. Edel; Aleksandar P. Ivanov, Measuring conductance switching in single proteins using quantum tunneling. Science Advances 2022, 8.
(7) Bintian Zhang; Eathen Ryan; Xu Wang; Stuart Lindsay, Probing Bioelectronic Connections Using Streptavidin Molecules with Modified Valency. Journal of the American Chemical Society 2021, 143, 15139-15144.
(8) Bintian Zhang; Weisi Song; Jesse Brown; Robert Nemanich; Stuart Lindsay, Electronic Conductance Resonance in Non-Redox-Active Proteins. Journal of the American Chemical Society 2020, 142, 6432-6438.
(9) Bintian Zhang; Hanqing Ding; Sohini Mukherjee; Weisi Song; Xu Wang; Stuart Lindsay, Engineering an Enzyme for Direct Electrical Monitoring of Activity. ACS Nano 2020, 14, 1360-1368.
(10) Bintian Zhang; Weisi Song; Pei Pang; Huafang Lai; Qiang Chen; Peiming Zhang; Stuart Lindsay, Role of contacts in long-range protein conductance. Proceedings of the National Academy of Sciences of the United States of America 2019, 116, 5886-5891.
(11) Bintian Zhang; Stuart Lindsay, Electronic Decay Length in a Protein Molecule. Nano Letters 2019, 19, 4017-4022.
(12) Bintian Zhang; Weisi Song; Pei Pang; Yanan Zhao; Peiming Zhang; Istvan Csabai; Gabor Vattay; Stuart Lindsay, Observation of giant conductance fluctuations in a protein. Nano Futures 2017, 1.
(13) Bintian Zhang; Lili Lu; Feng Huang; Zhang Lin, Ru(bpy)32+-mediated photoelectrochemical detection of bisphenol A on a molecularly imprinted polypyrrole modified SnO2 electrode. Analytica Chimica Acta 2015, 887, 59-66.
(14) Yiping Wu; Xiqiang Yang; Bintian Zhang; Liang-Hong Guo, An electrochemiluminescence biosensor for 8-oxo-7,8-dihydro-2′-deoxyguanosine quantification and DNA repair enzyme activity analysis using a novel bifunctional probe. Biosensors & Bioelectronics 2015, 69, 235-240.
(15) Lili Lu; Xianyang Yue; Fuquan Lin; Feng Huang; Bintian Zhang; Zhang Lin, Template-synthesized ultra-thin molecularly imprinted polymers membrane for the selective preconcentration of dyes. Journal of Materials Chemistry A 2015, 3, 10959-10968.
(16) Bintian Zhang; Lili Lu; Qichang Hu; Feng Huang; Zhang Lin, ZnO nanoflower-based photoelectrochemical DNAzyme sensor for the detection of Pb2+. Biosensors & Bioelectronics 2014, 56, 243-249.
(17) Yiping Wu; Bintian Zhang; Liang-Hong Guo, Label-Free and Selective Photoelectrochemical Detection of Chemical DNA Methylation Damage Using DNA Repair Enzymes. Analytical Chemistry 2013, 85, 6908-6914.
(18) Min-Jie Li; Yi-Ping Wu; Bin-Tian Zhang; Liang-Hong Guo, Detection and Application of DNA Abasic Sites. Chinese Journal of Analytical Chemistry 2013, 41, 965-972.
(19) Bintian Zhang; Liang-Hong Guo; Marc M. Greenberg, Quantification of 8-OxodGuo Lesions in Double-Stranded DNA Using a Photoelectrochemical DNA Sensor. Analytical Chemistry 2012, 84, 6048-6053.
(20) Bintian Zhang; Liang-Hong Guo, Highly sensitive and selective photoelectrochemical DNA sensor for the detection of Hg2+ in aqueous solutions. Biosensors & Bioelectronics 2012, 37, 112-115.
(21) BinTian Zhang; Xin Du; SuPing Jia; JunHui He; LiangHong Guo, Rapid assessment of DNA damage induced by polystyrene nanosphere suspension using a photoelectrochemical DNA sensor. Science China-Chemistry 2011, 54, 1260-1265.
代表性專利
1.“一種用于污染物毒性效應篩查的單分子蛋白電導檢測方法”,張斌田,姚靜靜,劉雨露,申請號:2025102159824,2025(中國專利)
2.“親氟疏水功能單體及其合成方法與應用、檢測電極及其制備方法”,張斌田,張坤,申請號:2024113789387,2024(中國專利)
3.“用于檢測醇類溶劑中含水量的絲網印刷電極及其制備方法”,張斌田,張坤,范志敏,公布號:CN118465019 A,2024(中國專利)
4.“一種用于全氟烷基和多氟烷基物質檢測的電極及其制備方法與應用”,張斌田,王尚卿,馬璐璐,鄭焰,公布號:CN117871631 A,2024(中國專利)
5. “Method for electronic detection and quantification of antibodies”, Stuart Lindsay,Bintian Zhang, WO2019217600A1, Nov. 14, 2021 (US/PCT)
6. “Bioelectronic circuits, systems and methods for preparing and using them”, Stuart Lindsay,Bintian Zhang,Hanqing Deng, WO2020160300A3, Sep. 10, 2020 (US/PCT)
7. “Direct electrical readout of nucleic acid sequences”, Stuart Lindsay,Bintian Zhang,Hanqing Deng, WO2020257654A1, Dec. 24, 2020 (US/PCT)
8. “Methods for sequencing biopolymers”, Stuart Lindsay, Eathen Ryan, Bintian Zhang, Xu Wang, US20220389502A1, Jun. 3, 2022 (US)