寧澄清
研究副教授
0755-88018396
ningcq@sustech.edu.cn
教育經(jīng)歷：
2011-2015 中南大學(xué)，藥物化學(xué)，醫(yī)學(xué)博士
2008-2011 中南大學(xué)，藥物化學(xué)，醫(yī)學(xué)碩士
2004-2008 江西中醫(yī)學(xué)院，藥學(xué)，理學(xué)學(xué)士
工作經(jīng)歷：
2021-至今 南方科技大學(xué)，研究副教授
2018-2020 南方科技大學(xué)，研究助理教授
2015-2017 南方科技大學(xué)，博士后
交叉研究領(lǐng)域：
研究方向主要為小分子藥物的設(shè)計、合成與活性研究，研究內(nèi)容主要包括運用計算機輔助藥物設(shè)計、有機合成及高通量活性篩選等技術(shù)手段來進(jìn)行抗腫瘤先導(dǎo)物和炎癥抑制劑的開發(fā)，探索其用于癌癥以及阿爾茨海默癥等神經(jīng)退行性疾病治療的可能。
代表文章：
Shengling Xie, Pan Ren, Jieping Hou, Chengqing Ning*, Jing Xu*. Stereoselective Synthesis of the ABC Ring System of Aspterpenacids. Journal of Organic Chemistry, 2018, 83, 14152-14157.
Chengqing Ning, Liumei Mo, Xuwei Chen, Wentong Tu, Jun Wu*, Shengtao Hou*, Jing Xu*. Triptolide derivatives as potential multifunctional anti-Alzheimer agents: Synthesis and structure–activity relationship studies, Bioorganic & Medicinal Chemistry Letters, 2018, 28(4): 689-693.
Wentong Tu, Chengqing Ning*, Jing Xu*. Enantioselective synthesis of (-)-phaseic acid, Organic Chemistry Frontiers, 2018, 5(1): 29-31.
Chengqing Ning, Cheng Lu, Liang Hu, Yanjing Bi, Lei Yao, Yujun He, Lifei Liu, Xiaoyu Liu*, Niefang Yu*. Macrocyclic compounds as anti-cancer agents: design and synthesis of multi-acting inhibitors against HDAC, FLT3 and JAK2. European Journal of Medicinal Chemistry. 2015, 95, 104-115.
Chengqing Ning，Wenyuan Huang, Wen Wu, Cheng Lu, Yujun He, Lei Yao, Lifei Liu, Xiaohe Zhen, Xiaoyu Liu*, Niefang Yu*. Discovery of novel potent HDAC inhibitors by structure-based optimization of cinnamic hydroxamic scaffold. Letters in Drug Design & Discovery. 2015, 12, 344-350.
Chengqing Ning, Yanjing Bi, Yujun He, Wenyuan Huang, Lifei Liu, Yi Li, Sihan Zhang, Xiaoyu Liu, Niefang Yu*. Design, synthesis and biological evaluation of di-substituted cinnamic hydroxamic acids bearing urea/thiourea unit as potent histone deacetylase inhibitors. Bioorganic & Medicinal Chemistry Letters. 2013, 23, 6432–6435.
