師資
個人簡介
劉超副教授2019年2月起任職南方科技大學,博士生導師。主要研究方向包括:骨骼干細胞力學生物學,骨組織工程及再生,功能性骨骼植入器械。在JBMR, Bone, Journal of Biomechanics的學術論文總引用次數1000余次。多次獲得國際骨科和骨骼組織研究協會青年研究者獎。最近在2019年國際生物科學及醫學工程大會(ICBME)獲得青年研究者獎。在入職南方科技大學一年內成功申請并主持深圳市基礎研究面上項目、廣東省高校青年創新人才項目。教學方面,承擔了《生物醫學工程(一)》、《骨骼組織工程》等本科生/研究生課程。
課題組主頁:https://abtrl.bme.sustech.edu.cn/
教育背景
2010年-2016年 加拿大多倫多大學生物材料與生物醫學工程研究所 博士
2008年-2010年 加拿大多倫多大學機械工程系 碩士
2003年-2008年 加拿大多倫多大學工程科學-生物醫學工程 本科
工作經歷
2024.11-至今 南方科技大學生物醫學工程系 副教授,博士生導師
2019年-2024.11 南方科技大學生物醫學工程系 助理教授,博士生導師
2016年-2019年 紐約大學生物醫學工程系,Langone醫學中心肌肉骨骼研究所 博士后
榮譽及獎勵
2019年,國際生物醫學工程會議年輕學者獎
2017年,國際肌肉骨骼研究協會聯合會Travel Grant
2016年,美國骨與礦物研究學會青年研究員Travel Grant
2010-2014年,加拿大衛生研究院Travel Grant
2011-2013年,安大略省研究生獎學金
2008,2010年,芭芭拉和弗蘭克米利根研究生獎學金
代表論文
1. Zhang, Jianing, Yanrong Tong, Yang Liu, Minmin Lin, Yao Xiao, and Chao Liu. "Mechanical loading attenuated negative effects of nucleotide analogue reverse-transcriptase inhibitor TDF on bone repair via Wnt/β-catenin pathway." Bone (2022): 116449.
2. Wang, Ziyan, Yang Liu, Jianing Zhang, Minmin Lin, Chufan Xiao, Haoying Bai, and Chao Liu. "Mechanical loading alleviated the inhibition of β2‐adrenergic receptor agonist terbutaline on bone regeneration." The FASEB Journal 35, no. 12 (2021): e22033.
3. Chao Liu, Pamela Cabahug‐Zuckerman, Christopher Stubbs, Martin Pendola, Cinyee Cai, Kenneth A. Mann, and Alesha B. Castillo. "Mechanical loading promotes the expansion of primitive osteoprogenitors and organizes matrix and vascular morphology in long bone defects." Journal of Bone and Mineral Research (2019). 34 (5), 896-910
4. Chao Liu and Alesha B. Castillo. "Targeting Osteogenesis-Angiogenesis Coupling for Bone Repair." JAAOS-Journal of the American Academy of Orthopaedic Surgeons 26.7 (2018): e153-e155.
5. Ma, Yu-Heng Vivian; Lam, Candy; Dalmia, Shreyash ; Gao, Peter; Young, Jacob; Middleton, Kevin; Liu, Chao; You, Lidan. “Mechanical regulation of breast cancer bone metastasis via direct and indirect osteocyte signalling in vitro” Journal of Cellular Biochemistry. 2018, 119 (7), 5665-5675
6. Chao Liu, Robert Carrera, Vittoria Flamini, Lena Kenny, Pamela Cabahug-Zuckerman, Benson George, Daniel Hunter, Bo Liu, Gurpreet Singh, Philipp Leucht, Kenneth A Mann, Jill A Helms, Alesha B Castillo, “Effects of mechanical loading on cortical defect repair using a novel mechanobiological model of bone healing” Bone. 2018, 108, pp. 145-155.
7. Qian, Weiyi; Gong, Lanqi; Cui, Xin; Zhang, Zijing; Bajpai, Apratim; Liu, Chao; Castillo, Alesha; Teo, Jeremy; Chen, Weiqiang “Nanotopographic regulation of human mesenchymal stem cell osteogenesis” ACS Applied Materials & Interfaces. 2017, 9 (48), pp 41794–41806
8. Bradaschia-Correa V, Josephson AM, Mehta D, Mizrahi M, Neibart SS, Liu C, Kennedy OD, Castillo AB, Egol KA, Leucht P. “The selective serotonin re-uptake inhibitor fluoxetine directly inhibits osteoblast differentiation and mineralization during fracture healing in mice.” Journal of Bone and Mineral Research. 32(4) 2017: 821–833
9. Chao Liu, Xin Cui, Thomas Michael Ackermann, Vittoria Flamini, Weiqiang Chen, Alesha Castillo “Osteoblast-Derived Paracrine Factors Regulate Angiogenesis in Response to Mechanical Stimulation” Integrative Biology 8(7) 2016, 785-794
10. Chao Liu, Xiaoqing Zhang, Michael Wu, Lidan You “Mechanical Regulation of Osteocyte Responses to Physical Damage in vitro” Journal of Biomechanics 2015. 48(16): 4221-4228
11. Ashutosh Parajuli*, Chao Liu*, Wen Li*, Xiaoyu Gu, Xiaohan Lai, Christopher Price, Lidan You, X. Lucas Lu, Liyun Wang “Bone's Responses to Mechanical Loading are Impaired in Type 1 Diabetes” Bone 81 (2015) 152–160. (*Equal contributions)
12. Jia-Ning Zhang, Yan Zhao, Chao Liu, Elizabeth S. Han, Xue Yu, Darcy Lidington, Steffen-Sebastian Bolz, Lidan You “The Role of the Sphingosine-1-Phosphate Signaling Pathway in Osteocyte Mechanotransduction Bone” Bone 79 (2015) 71-78.
13. Chao Wei, Beiyuan Fan, Deyong Chen, Chao Liu, Yuanchen Wei, Bo Huo, Lidan You, Junbo Wang and Jian Chen “Osteocyte Culture in Microfluidic Devices” Biomicrofluidics. 9, 014109 (2015)
14. Wing-Yee Cheung, Chao Liu, Craig A. Simmons, Lidan You, “Osteocyte Apoptosis is Mechanically Regulated and Induces Angiogenesis In Vitro”, Journal of Orthopedic Research, 2011 April ;29(4):523-30
15. Chao Liu, Yan Zhao, Wing-Yee Cheung, Ronak Gandhi, Liyun Wang, Lidan You “Effects of cyclic hydraulic pressure on osteocytes” Bone. 46 (5), May 2010, pp. 1449-1456
16. Chao Liu, Alesha B. Castillo, “Targeting Osteogenesis-Angiogenesis Coupling for Bone Repair” Journal of the American Academy of Orthopaedic Surgeons. 2018 (invited review)
17. Jan-Hung Chen*, Chao Liu*, Lidan You, Craig A. Simmons, “Boning up on Wolff’s Law: Mechanical regulation of the cells that make and maintain bone” Journal of Biomechanics 43 (1), pp. 108-118 (*Equal contributions)