師資
李婷婷，南方科技大學生物醫學工程系研究助理教授，2023年獲得南方科技大學理學博士學位，主要研究方向為生物醫學光學成像，致力于快速、大視場、高分辨率光聲成像技術及以其為核心的多模態光學成像技術的研發，并將其廣泛應用于生命科學領域的基礎和前沿研究中。迄今為止，在Nature Communications, Laser & Photonics Reviews, Optics Letters, Advanced Functional Materials, Advanced Science, Biomedical Optics Express等國際期刊上共發表SCI論文24篇，其中一作及通訊作者論文11篇；申請或授權專利4項；主持國自然青年科學基金項目C類1項、深圳市優秀科技創新人才培養項目1項，作為核心成員或骨干參與國家自然科學基金重點項目、中華人民共和國科學技術部重點研發計劃、深圳市基礎研究重點項目、深圳市醫學科學院前沿探索項目等7項。
教育背景
2019.09～2023.06 博士， 生物學，南方科技大學
2014.09～2017.06 碩士， 電子與通信工程，電子科技大學
2010.09～2014.06 學士， 電子信息科學與技術，河南科技大學
工作經歷
2025.09～至今研究助理教授，南方科技大學
2023.07～2025.09 博士后， 物理學，南方科技大學
2018.04～2019.08 科研助理， 南方科技大學
2017.07～2018.03 軟件工程師，珠海和佳醫療設備股份有限公司
獎勵情況
1. 優秀研究生，南方科技大學，2023
2. 國家獎學金，南方科技大學，2022
3. 優秀學生報告獎，中國光學學會，2021
承擔項目
1. 國家自然科學基金委，青年科學基金項目C類，62505125，多自由度超快光聲腦功能成像技術研究，2026.01-2028.12，30萬元， 主持
2. 深圳市科技創新委員會，優秀科技創新人才培養（博士基礎研究啟動），RCBS20231211090802011，基于光聲擴展顯微技術的亞細胞結構成像研究，202406-2026.06，30萬元，主持
3. 國家自然科學基金委，重點項目，62435008，多參量大視場快速光聲子宮內窺體成像研究，2025.01-2029.12，231萬元，參與
4. 國家自然科學基金委，青年科學基金項目，61701076，用于腦出血檢測的微波熱聲成像技術研究，2018.01-2020.12，23萬元，參與
5. 中華人民共和國科學技術部，重點研發計劃，2024YFF0507200，光學多模態信息腦活體成像關鍵問題研究，2024.12-2029.12，1432.2萬元，參與
6. 中華人民共和國科學技術部，重點研發計劃，2023YFF0715300，超分辨光聲成像分析儀，2023.12-2026.11，600萬元，參與
7. 深圳市科技創新委員會，基礎研究專項基礎研究重點項目，JCYJ20241202124916023，新型快速全腦高分辨率成像技術和方法研究，2024.12-2027.12，200萬元，參與
8. 深圳市科技創新委員會，基礎研究專項重點項目，20231116104616001，大視場光聲內窺顯微技術機理研究，2023.10-2026.09，100萬元，參與
9. 深圳市科技創新委員會，基礎研究專項基礎研究面上項目，JCYJ20220530114010023，人工超表面調控下的微波熱聲成像技術及其在乳腺癌早期診斷中的應用研究，2022.10-2025.10，30萬元，參與
期刊論文（*通訊作者, #共同一作）
1. Wei Qin#, Tingting Li#, Linyang Li#, Tian Jin, Baochen Li, Weizhi Qi, Yifan Chen, Haoyang Li, Shijie Ruan, Heng Guo, Xiao Liang, Lei Xi*, A cortex-wide multimodal microscope for simultaneous Ca2+ and hemodynamic imaging in the awake mouse, Nature communications, Accepted.
2. Tingting Li#, Heng Guo#, Ye Liu#, Weizhi Qi, Changfeng Wu, Lei Xi*, All-in-One Photoacoustic Theranostics Using Multi-Functional Nanoparticles, Advanced Functional Materials, 2022, 32(6), 2107624.
3. Tingting Li#, Xinrui Gong#, Heng Guo, Lei Xi*, Photoacoustic expansion microscopy of melanosomes, Optics Letters, 2024, 49(4), 798-801.
4. Wei Qin#, Tingting Li#, Yifan Chen#, Xiao Liang, Linyang Li, Heng Guo, Weizhi Qi*, Lei Xi*, High-efficiency photoacoustic microscopy for ultrafast hemodynamic imaging, Laser & Photonics Reviews, 2025, 2401545, doi: 10.1002/lpor.202401545. Publish Online
5. Yuanlong Zhao, Tingting Li*, Heng Guo, Rui Hu, Lei Xi*, Long-term Assessment of Cutaneous Inflammation and Treatment using Optical Resolution Photoacoustic Microscopy, Biomedical Optics Express, 2023, 174(9), 4775-4789.
6. Jun Wang#, Tingting Li#, Jen-shyang Ni#, Heng Guo, Tianyi Kang, Zeshun Li, Menglei Zha, Songbo Lu, Chen Zhang, Weizhi Qi, Lei Xi*, Kai Li*, Photoacoustic Force-Guided Precise and Fast Delivery of Nanomedicine with Boosted Therapeutic Efficacy, Advanced Science, 2021, 8(16), 2100228.
7. Zeshun Li#, Tingting Li#, Chen Zhang#, Jen-shyang Ni, Yaoyao Ji, Aihui Sun, Dinglu Peng, Weijun Wu, Lei Xi*, Kai Li*, A multispectral Photoacoustic Tracking Strategy for Wide-field and Realtime Monitoring of Macrophages in Inflammation, Analytical Chemistry, 2021, 93(24), 8467-8475.
8. Weizhi Qi#, Tingting Li#, Chen Zhang#, Fei Liu, Jun Wang, Dandan Chen, Xiaofeng Fang, Changfeng Wu*, Kai Li*, Lei Xi*, Light-Controlled Precise Delivery of NIR-Responsive Semiconducting Polymer Nanoparticles with Promoted Vascular Permeability, Advanced Healthcare Materials, 2021, 10(9), 2100569.
9. Huilin Xie#, Chen Zhang#, Tingting Li#, Lianrui Hu, Jianquan Zhang, Heng Guo, Zhao Liu, Dinglu Peng, Zeshun Li, Weijun Wu, Ji Gao, Zhenyu Bi, Jinghan Wang, Pengfei Zhang, Ryan T. K. Kwok, Jacky W. Y. Lam, Zhihong Guo, Lei Xi*, Kai Li*, Ben Zhong Tang*, Fast Delivery of Multifunctional NIR-II Theranostic Nanoaggregates Enabled by the Photoinduced Thermoacoustic Process, Advanced Science, 2023, 10(19), 2301104.
10. Ziyi Xu#, Mingkun Lv#, Jingkai Yang#, Tingting Li#, Jiahui Lv, Jiaxin Li, Hongjun Xiao, Yicheng Yang, Siyu Zhou, Xuan Tan, Li Cheng, Heng Guo, Lei Xi*, Pan-Lin Shao*, Bo Zhang*, An efficient heat and peroxynitrite generating nanoplatform for multimodal imaging-guided precision tumor phototherapy, Aggregate, 2025, e70040, doi: 10.1002/agt2.70040. Publish Online
11. Lin Huang#, Tingting Li#, Huabei Jiang*, Technical Note: Thermoacoustic imaging of hemorrhagic stroke: A feasibility study with a human skull, Medical Physics, 2017, 44(4), 1494-1499.
12. Xiao Liang#, Yuanlong Zhao#, Linyang Li, Hongdian Sun, Wei Qin, Tingting Li , Heng Guo, Weizhi Qi, Lei Xi*, Non-telecentric photoacoustic microscopy for multi-scale imaging, Photoacoustics, 2025, 45, 100750.
13. Yujie Wang#, Linyang Li#, Weizhi Qi, Wei Qin, Tian Jin, Tingting Li, Pavel Subochev, Lei Xi*, Non-telecentric photoacoustic microscopy for multi-scale imaging, Optics Letters, 2024, 49(10), 2637-2640.
14. Linyang Li#, Wei Qin#, Tingting Li, Junning Zhang, Baochen Li, Lei Xi*, High-speed Adaptive Photoacoustic Microscopy, Photonics Research, 2023. 11(12), 2084-2092.
15. Qiang Liu, Xiao Liang, Tingting Li, Weian Chao, Weizhi Qi, Tian Jin, Yubin Gong, Huabei Jiang, Lei Xi*, Split ring resonator topology based microwave induced thermoacoustic imaging (SRR-MTAI), IEEE Transactions on Medical Imaging, 2023, 42(8), 3250647.
16. Heng Guo#, Qian Chen#, Tingting Li, Desheng Sun, Lei Xi*, Photoacoustic-triggered nanomedicine delivery to internal organs using a dual-wavelength laparoscope, Journal of Biophotonics, 2022, 15(9), e202200116.
17. Aihui Sun#, Yaoyao Ji#, Yaxi Li, Wenhui Xie, Zhihe Liu, Tingting Li, Tian Jin, Weizhi Qi, Kai Li, Changfeng Wu, Lei Xi*, Multi-color Photoacoustic volumetric imaging of subcellular structures, ACS Nano, 2022, 16(2), 3231-3238.
18. Yongchao Wang#, Ruoxi Zhang#, Qian Chen, Heng Guo, Xiao Liang, Tingting Li, Weizhi Qi, Lei Xi*, Visualization of blood-brain barrier disruption with dual-wavelength high-resolution photoacoustic microscopy, Biomedical Optics Express, 2022, 13(3), 1537-1550.
19. Xiaoxia Song, Rongxin Qian, Tingting Li, Wei Fu, Lijun Fang, Yuzhen Cai, Heng Guo, Lei Xi, U Kei Cheang*, Imaging-Guided Biomimetic M1 Macrophage Membrane-Camouflaged Magnetic Nanorobots for Photothermal Immunotargeting Cancer Therapy, ACS Applied Materials & Interfaces, 2022, 14(51), 56548-56559.
20. Aihui Sun, Tingting Li, Tian Jin, Yaxi Li, Kai Li, Chaolong Song, Lei Xi*, Acoustic Standing Wave Aided Multiparametric Photoacoustic Imaging Flow Cytometry, Analytical Chemistry, 2021, 93(44), 14820-14827.
21. Tianyi Kang#, Jen-Shyang Ni#, Tingting Li, Jun Wang, Zeshun Li, Yaxi Li, Menglei Zha, Chen Zhang, Xue Wu, Heng Guo, Lei Xi, Kai Li*, Efficient and Precise Delivery of MicroRNA by Photoacoustic Force Generated from Semiconducting Polymer-Based Nanocarriers, Biomaterials, 2021, 275, 120907.
22. Yanan Gao, Zhihua Li, Yin Hong, Tingting Li, Xiaoyan Hu, Luyao Sun, Zhengchang Chen, Zijian Chen, Zhiheng Luo, Xin Wang, Jian Kong, Guanglei Li, Hsing-Lin Wang, Hwa Liang Leo, Hanry Yu, Lei Xi, Qiongyu Guo*, Decellularized liver as a translucent ex vivo model for vascular embolization evaluation, Biomaterials, 2020, 240, 119855.
23. Fei Liu#, Tian Jin#, Ruopeng Yan, Tingting Li, Biao Hu, Lei Yao, Tianye Huang, Chaolong Song*, Lei Xi*, An opto-acousto-fluidic microscopic system with a high spatiotemporal resolution for microfluidic applications, Optics Express, 2019, 27(2), 1425-1432.
24. Zhihui Chi, Yuan Zhao, Jinge Yang, Tingting Li, Guang Zhang, Huabei Jiang*, Thermoacoustic Tomography of In Vivo Human Finger Joints, IEEE Transactions on Biomedical Engineering, 2019, 66(6), 1598-1608.
學術會議
1. 李婷婷，齊偉智，吳長鋒*，奚磊*，基于光聲效應的藥物遞送和腫瘤診療研究，BPC 2022 (口頭報告)
2. Tingting Li, Xinrui Gong, Weizhi Qi, Lei Xi*, Ultrafast Random-Access Scanning Photoacoustic Microscopy, PIBM 2021 (海報+口頭報告)
3. 李婷婷，齊偉智，王俊，康天懌，吳長鋒*，李凱*，奚磊*，基于光聲精準遞送納米粒子的腫瘤診療，COS 2021 (海報)
申請專利
1. 奚磊，王永超，郭恒，張若曦，李婷婷，基于雙波長光聲顯微成像的血腦屏障損傷評估裝置及方法，ZL 202111083736.6，發明專利，中國，2023-09-01
2. 奚磊，李婷婷，郭恒，齊偉智，一種光聲顯微成像診療裝置及其使用方法，202011615857.6，發明專利，中國，2020-12-30
3. 奚磊，李婷婷，齊偉智，一種基于隨機訪問掃描的光聲顯微成像裝置及方法，202311350742.2，發明專利，中國，2023-10-18
4. 奚磊，王玉潔，李林陽，齊偉智，秦偉，李婷婷，基于無級調節中繼光路的多尺度光聲顯微鏡及其成像方法，202410208119.1，2024-02-26